منابع مشابه
Chromatin Unfolds
sites near the ends are most accessible, but even sites near the center of the nucleosome can be attacked, National Institute of Diabetes and Digestive and Kidney Diseases though less readily. The results are consistent with a free energy of binding of DNA to the nucleosome surface National Institutes of Health Bethesda, Maryland 20892-0540 of 0.1–0.15 kcal/mol bp in the range of ionic strength...
متن کاملThe Story Unfolds
The middle of 2007 saw what may, with time, turn out to be the single most important discovery in the genetics of cardiovascular diseases. Within a few weeks, 4 independent genomewide association studies reported the association of the same locus on chromosome 9p21 with coronary artery disease (CAD) and myocardial infarction (MI).1– 4 In fact, of the hundreds of thousands single-nucleotide poly...
متن کاملFemale genital appearance: "normality" unfolds.
OBJECTIVE To describe variations in genital dimensions of normal women. DESIGN Observational cross-sectional study. SETTING Elizabeth Garrett Anderson Hospital, University College Hospital NHS Trust, London, UK. POPULATION Fifty premenopausal women having gynaecological procedures not involving the external genitalia under general anaesthetic. METHODS A cross sectional study using digit...
متن کاملReversing Neurodegeneration:A Promise Unfolds
mamoto et al. address in their elegantly simple study. Few human ills have seemed as hopelessly intractable They first established a line of mice carrying a transgene as neurodegenerative diseases. Until recently, there has with the tetO bidirectional promoter flanked by a lacZ been little reason for optimism that we might halt the reporter gene and exon 1 of huntingtin (htt) containing degener...
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Knowing the true rate of death from covid-19 will help us fight the pandemic, but for the moment it eludes us, reports Michael Le Page.
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ژورنال
عنوان ژورنال: Nature Reviews Molecular Cell Biology
سال: 2002
ISSN: 1471-0072,1471-0080
DOI: 10.1038/nrm884